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2 Answers - Posted in: depakote, paxil, soma, pain, tramadol - Answer: From what I found it looks like you can but beware of drowsiness. Is there ... A Major Drug Interaction exists between Carisoprodol Compound and tramadol. View detailed information regarding this drug interaction. I used to be a big tramadol plus soma every day kind of guy. By itself tramadol just makes me feel like shit, but for some reason when combined with soma there is a ... We studied 155 people who take Tramadol and Carisoprodol from FDA. Drug interactions are found. See what they are, when they happen and for whom.

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